Dr. Qunying Yuan Biography

Research

I am testing the potential of using biological entities as a platform, such as microorganisms and plants, to synthesize metallic nanoparticles. In addition, I am also exploring the potential applications of natural products as therapeutic agents or food additives.  

Area of Expertise and /or Research:  

Molecular biology, Synthetic Biology, Identification of antimicrobial and antioxidant agents, Physiology,  

Education

• Ph.D. in Molecular, Cellular and Biochemical Pharmacology, College of Medicine, University of Cincinnati, Cincinnati, OH, USA, 2007. 

  Doctoral Candidate in Internal Medicine, Sun Yat-Sen University of Medical Sciences, Guangzhou, China, 1999 

  Master of Internal Medicine, Sun Yat-Sen University of Medical Sciences, Guangzhou, China, 1998 

  Bachelor in Medical Sciences JiangXi Medical College, Jiangxi, China, 1992 

   

  Professional Preparation 

  Ph.D. in Molecular, Cellular and Biochemical Pharmacology, College of Medicine, University of Cincinnati, Cincinnati, OH, USA, 2007. 

  Doctoral Candidate in Internal Medicine, Sun Yat-Sen University of Medical Sciences, Guangzhou, China, 1999 

  Master of Internal Medicine, Sun Yat-Sen University of Medical Sciences, Guangzhou, China, 1998 

  Bachelor in Medical Sciences JiangXi Medical College, Jiangxi, China, 1992 

   

  Appointments 

  Aug. 2016 - Present: Associate Professor, Department of Biological and Environmental 

  Sciences, Alabama A&M University, Normal, AL. 

  Oct. 2007 - Jul. 2016: Research Scientist, iXpressGenes, Inc. Huntsville, AL 

  July. 1998 - Aug. 1999: Physician, Internal Medicine Suzhou Fourth Hospital, Jiangsu, China 

  Aug. 1992 - Aug. 1995: Physician, Internal Medicine Jiangxi Province Hospital, Jiangxi, China 

Publications

• Peer-Reviewed Publications in Conference Proceedings 

  1. J. Kimbrough, S. Chance, B. Whitaker, Z. Duncan, K. Davis, A. Henderson, Z Xiao, Q. Yuan, F. Camino. “Deposition and Alignment of Carbon Nanotubes with Dielectrophoresis for Fabrication of Carbon Nanotube Field-Effect Transistors”, IEEE Xplore: 2018 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO), 308-311 (2018).

  Peer-reviewed Publications in Journals  

  1. Manjula Bomma, Lam Duong, Srinivas Rao Mentreddy, Florence Okafor, Qunying Yuan*. Comparison of Phytochemical Composition, Free Radical Scavenging Activity, and Antimicrobial Activity of Selected Herbs Against Two Foodborne Pathogenic Bacteria. American Journal of Biomedical and Life Sciences. (Accepted) 
  2. Yuan, Qunying*; Bomma, Manjula; Xiao, Zhigang. "Enhanced Extracellular Synthesis of Gold Nanoparticles by Soluble Extracts from Escherichia coli Transformed with Rhizobium tropici Phytochelatin Synthase Gene" Metals 2021. 11(3): 472. https://doi.org/10.3390/met11030472
  3. Xianyan Kuang; Rong Xiao; Xinhua Xiao; Qunying Yuan; Thomas Sauer; Dedrick Davis. Soil carbon dioxide emissions in a sorghum field: Row position and growth stage effects. Agrosyst Geosci Environ. 2021; 4:e20138. https://doi.org/10.1002/agg2.20138
  4. Joevonte Kimbrough; Lauren Williams; Qunying Yuan; and Zhigang Xiao. Dielectrophoresis-Based Positioning of Carbon Nanotubes for Wafer-Scale Fabrication of Carbon Nanotube Devices. Micromachines 2021;12:12. https://dx.doi.org/10.3390/mi12010012
  5. Qunying Yuan*, Manjula Bomma Haley Hill, Zhigang Xiao. Expression of Rhizobium tropici phytochelatin synthase in Escherichia coli resulted in increased bacterial selenium nanoparticle synthesis. Journal of Nanoparticle Research. 2020. 22(12). DOI: 10.1007/s11051-020-05095-z
  6. Qunying Yuan*, Manjula Bomma, Zhigang Xiao. Enhanced Silver Nanoparticle Synthesis by E. coli Transformed with Candida albicans Metallothionein Gene. Materials 2019, 12, 4180; doi:10.3390/ma12244180
  7. M. Pusey, J. Barcena, M. Morris, A.j Singhal, Q. Yuan, J. Ng. Trace fluorescent labeling for protein crystallization. Acta Cryst. 2015. F71, 806–814
  8. S. Boncompagni, M. Thomas, JR. Lopez, PD. Allen, Q. Yuan, EG. Kranias, C. FranziniArmstrong, CF. Perez. Triadin/Junctin double null mouse reveals a differential role for Triadin and Junctin in anchoring CASQ to the jSR and regulating Ca2+ homeostasis. PLoS One. 2012;7(7):e39962
  9. WF Cai, T Pritchard, S Florea S, CK Lam, P Han, X Zhou, Q Yuan, SE Lehnart, PD Allen, Kranias EG. Ablation of junctin or triadin is associated with increased cardiac injury following ischaemia/reperfusion. Cardiovasc Res. 2012, 94(2):333-41
  10. K Haghighi, T Pitchard, Bossuyt J, Waggoner JR, Q Yuan, GC Fan, H Osinska, A Anjak, J Rubinstein, J Robbins, DM Bers, EG Kranias. The human phospholamban Arg14-deletion mutant localizes to plasma membrane and interacts with the Na/K-ATPase. J Mol Cell Cardiol. 2012; 52(3):773-82.
  11. BA Altschafl, DA Arvanitis, O Fuentes, Q Yuan, EG Kranias, HH Valdivia. Dual role of junctin in the regulation of ryanodine receptors and calcium release in cardiac ventricular myocytes. J Physiol. 2011; 589(Pt 24):6063-80.
  12. Q. Yuan, M. Dong, X. Ren, X. Zhou, W. K. Jones, HS Wang, G. Chu, and EG. Kranias. Partial Downregulation of Junctin Enhances Cardiac Calcium Cycling Without Eliciting Ventricular Arrhythmias in Mice. Am J Physiol Heart Circ Physiol. 2009, 296(5):H1484-90.
  13. A Diwan, SJ Matkovich, Q Yuan, W Zhao, A Yatani, JH Brown, JD. Molkentin, EG. Kranias, G. W Dorn II. Endoplasmic Reticulum-mitochondria Crosstalk in NIX-mediated Murine Cell Death. J Clin Invest. 2009, 119(1):203-12
  14. G-C Fan, Q Yuan, EG. Kranias. Regulatory Roles of Junctin in SR Ca Cycling and Myocardial Function (Review). Trends in Cardiovascular Medicine, 2008; 18(1):1-5
  15. Q Yuan, G-C Fan, M Dong, B Altschafl, A Diwan, X Ren, W Zhao, J. R. Waggoner, L. R. Jones, K. W. Jones, D. M. Bers, G. W Dorn II, H-S Wang, H. H. Valdivia, G Chu, and E. G. Kranias. Sarcoplasmic Reticulum Calcium Overloading in Junctin Deficiency Enhances Cardiac Contractility, but Increases Ventricular Automaticity. Circulation, 2007; (115): 300-309
  16. G-C Fan, Q Yuan, W Zhao, G Chu and EG Kranias (Co-first author). Junctin Is a Prominent Regulator of Contractility in Cardiomyocytes. Biochem Biophys Res Commun. 2007; 352(3):617-22
  17. G-C Fan, Q Yuan, G Song, Y Wang, J Qian, P Nicolaou, X Zhou, G Chen, M Ashraf, E G. Kranias. Small heat-shock protein Hsp20 attenuates beta-agonist-mediated cardiac remodeling through apoptosis signal-regulating kinase 1. Circ Res. 2006 Nov 24; 99(11):1233-42
  18. W Zhao, Q Yuan, A Pathak, G Chu, H S. Hahn, Y Marreez, F Syed, G W. Dorn II, E G. Kranias. The Presence of Lys27 Instead of Asn27 in Human Phospholamban Promotes Sarcoplasmic Reticulum Calcium-ATPase Superinhibition and Cardiac Remodeling. Circulation. 2006 113(7):995-1004.
  19. G-C Fan, X Ren, J Qian, Q Yuan, P Nicolaou, Y Wang, K Jones, G Chu, E G. Kranias. A Novel Cardioprotective Role of a Small Heat-Shock Protein Hsp20 against Ischemia Reperfusion Injury. Circulation, 2005 111(14):1792-9
  20. G-C Fan, G Chu, B Mitten, Q Song, Q Yuan, E G. Kranias. Small heat-shock protein Hsp20 phosphorylation inhibits beta-agonist- induced cardiac apoptosis. Circ Res.2004, 94(11):1474-82

  *: corresponding author 

   

  Abstracts and Presentations in National and International Conferences  

  Oral Presentations 

  1. The 2019 1890 ARD Biennial Research Symposium. Mar.30 – Apr. 3, 2019. Jacksonville, FL 

  Title: Soil Carbon Dioxide Emission in a Sorghum Field during Growing Season.   

  Author: Rong Xiao, Xianyan Kuang, Dedrick Davis, Xinhua Xiao, Qunying Yuan 

  2. The American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America Annual International Meeting, Oct. 22-25, 2017, Tampa, FL

  Title: Real Time Evapotranspiration Monitoring and Forecasting Based on Alabama Mesonet. 

  Author: Xinhua Xiao1, Xianyan Kuang, Dedrick D. Davis, Qunying Yuan and Monday Mbila 

  3. America Heart Association Scientific sessions. Nov. 7-11, 2004, New Orleans, LA

  Title: Ablation of junctin by gene targeting results in enhanced cardiac contractility and calcium kinet-ics 

  Author: Qunying Yuan, Guo-chang Fan, Xiaoyin Sun, Wen Zhao, Harvey Hahn, Hong-Sheng Wang, Larry R. Jones, Guoxiang Chu and Evangilia G. Kranias.  

  4. America Heart Association Scientific sessions. Nov. 13-16, 2005, Dallas, TX

  Title: Junctin deficiency is associated with arrhythmias in junctin knockout mice                               

  Author: Qunying Yuan, Beth Altschafl, Min Dong, Guo-chang Fan, Larry R. Jones, Hong-Sheng Wang, Hector H. Valdivia, Guoxiang Chu and Evangelia G. Kranias 

   

  Poster Presentations: 

  1. The 2020 Virtual MRS Fall Meeting, Nov. 27- Dec. 4. 2020

  Title: Nanoparticle Synthesis by Engineered E. coli Cells Transformed with a Phytochelatin Synthase Gene. 

  Author: Haley Hill, Manjula Bomma, Qunying Yuan, Zhigang Xiao 

  2. The 2020 ERN Conference in STEM, Washington, D.C., February 6-8, 2020

  Title: Metallic Nanoparticle Synthesis by Engineered E. coli Cells Transformed with Metallothionein Gene. 

  Author: Mhiret Girma, Manjula Bomma, Qunying Yuan, Zhigang Xiao 

  3. The 2019 MRS Fall Meeting, Dec. 1-6, 2019, Boston, MA. 

  Title: Enhanced Silver Nanoparticle Synthesis by E. coli Transformed with Metallothionein Gene. 

  Author: Qunying Yuan, Brittany Batiste, Zhigang Xiao 

  4. 13th Annual STEM Day, Apr. 12, 2019, Alabama Agricultural and Mechanical University.

  Title: Soil Carbon Dioxide Emission in a Sorghum Field during Growth Seasons. 

  Author: Rong Xiao, Xianyan Kuang, Dedrick Davis, Xinhua Xiao, Qunying Yuan  

  5. The 2018 MRS Fall Meeting, Nov. 2018, Boston, MA.

  Title: Dielectrophoresis-Based Fabrication of Carbon Nanotube-Based Electronic Device.  

  Author: Joevonte Kimbrough, Sam Chance, Brandon Whitaker, Kenneth Davis, Alandria Henderson, Qunying Yuan, and Zhigang Xiao.  

  6. The AVS 65nd International Symposium & Exhibition Oct. 2018, Long Beach, CA. 

  Title: Fabrication of Carbon Nanotube-Based Electronic Devices with the Dielectrophoresis Method 

  Author: Joevonte Kimbrough, Sam Chance, Brandon Whitaker, Zackary Duncan, Kenneth Davis, Alandria Henderson, Qunying Yuan and Zhigang Xiao  

  7. 12th Annual STEM Day, Apr. 13, 2018, Alabama Agricultural and Mechanical University. 

  Title: Effects of Tillage and Residue Managements on Soil Microbial Community, Carbon Dioxide Effluxes and Soil Physical Properties in a Biofuel Sorghum Feedstock Production System 

  Author: Rong Xiao, Xinhua Xiao, Xianyan Kuang, Dedrick Davis, Qunying Yuan 

  8. The American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America Annual International Meeting, Oct. 22-25, 2017, Tampa, FL

  Title: The Effects of Surface Soil Heat Flux on the Estimation of Evapotranspiration. 

  Author: Xinhua Xiao, Xianyan Kuang, Dedrick D. Davis and Qunying Yuan