Food Biotechnology Laboratory
Associate Professor of Food Biotechnology
Agricultural Research Center, Room 114
Phone: (256) 372-4168
Email: stylianos.fakas@aamu.edu
Research
We study the regulation of lipid metabolism in the model oleaginous yeast Yarrowia lipolytica.
People
Stylianos Fakas
Dr. Fakas received his BS and PhD from the Agricultural University of Athens, Greece and his Master's degree from the National University of Athens, Greece. He completed his postdoctoral training in the laboratory of Dr. George Carman at Rutgers University where he studied the regulation of phospholipid metabolism in the yeast Saccharomyces cerevisiae. In 2014, he joined the faculty of Food and Animal Sciences at Alabama A&M University. He is currently Associate Professor of Food Biotechnology and serves as the advisor of the Alabama A&M student chapter of the American Society of Biochemistry and Molecular Biology (ASBMB).
Publications
View Stylianos Fakas' Google Scholar Profile
2024
- CARMON T., HILL N.T., SRIPATHI V.R., GOSSETT Z.B., FAKAS S.: The PAH1-encoded phosphatidate phosphatase of Yarrowia lipolytica differentially affects gene expression and lipid biosynthesis. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 2024, 1869:159544. DOI:10.1016/j.bbalip.2024.159544
2020
- UKEY, R., CARMON, T., HARDMAN, D., HILL, N., FAKAS, S., The Yarrowia lipolytica PAH1 homolog contributes but is not required for triacylglycerol biosynthesis during growth on glucose. Yeast, 2020, 37: 93–102. DOI: 10.1002/yea.3447
2018
- HARDMAN, D., UKEY, R., FAKAS, S., Phosphatidate phosphatase activity is induced during lipogenesis in the oleaginous yeast Yarrowia lipolytica. Yeast, 2018, 35: 619-625. DOI: 10.1002/yea.3353
2017
- HARDMAN, D., MCFALLS, D., FAKAS, S., Characterization of phosphatidic acid phosphatase activity in the oleaginous yeast Yarrowia lipolytica and its role in lipid biosynthesis. Yeast, 2017, 34: 83-91. DOI: 10.1002/yea.3216
- FAKAS, S., Lipid biosynthesis in yeasts: A comparison of the lipid biosynthetic pathway between the model non‐oleaginous yeast Saccharomyces cerevisiae and the model oleaginous yeast Yarrowia lipolytica. Engineering in Life Sciences, 2017, 17: 292–302. DOI: 10.1002/elsc.201600040
2016
- HARDMAN, D., FAKAS, S., Polyunsaturated Fatty Acids as Dietary Supplements: Biological Activities and Sources. International Journal of Clinical Nutrition & Dietetics, 2016, 2:113. DOI: 10.15344/2456-8171/2016/113
2013
- SEMBONGI, H., MIRANDA, H., HAN, G.-S., FAKAS, S., GRIMSEY, N., VENDRELL, J., CARMAN, G. M., SINIOSSOGLOU, S., Distinct roles of the phosphatidate phosphatases lipin 1 and 2 during adipogenesis and lipid droplet biogenesis in 3T3-L1 cells. Journal of Biological Chemistry, 2013, 288: 34502-34513. DOI: 10.1074/jbc.M113.488445
- QIU, Y., FAKAS, S., HAN, G.-S., BARBOSA, A. D., SINIOSSOGLOU, S., CARMAN, G. M., Transcription factor Reb1p regulates DGK1-encoded diacylglycerol kinase and lipid metabolism in Saccharomyces cerevisiae. Journal of Biological Chemistry, 2013, 288:29124-29133. DOI: 10.1074/jbc.M113.507392
2012
- SOTO-CARDALDA, A., FAKAS, S., PASCUAL, F., CHOI, H-S., CARMAN, G.M., Phosphatidate phosphatase plays role in zinc-mediated regulation of phospholipid synthesis in yeast. Journal of Biological Chemistry, 2012, 287:968-977. DOI: 10.1074/jbc.M111.313130
| Class Number | Class Name | Level |
|---|---|---|
| FAS 453 & 553 | Agricultural Biochemistry | Dual level |
| FAS 615 | Food Enzymes | Graduate |
| FAS 671 | Introduction to Biotechnology | Graduate |
| FAS 771 | Advanced Food Biotechnology | Graduate |
| FAS 780 | Functional Foods and Nutraceuticals | Graduate |
| Name | Classification | Year |
|---|---|---|
| Derell Hardman | Graduate (Master's & Ph.D.) | 2014-24 |
| Vanessa Kishasha | Graduate (Master's) | 2017-19 |
| Rahul Ukey | PostDoctoral | 2016-19 |
| Taiwo Adebayo | Graduate (Master's) | 2018-20 |
| Taylor Carmon | Graduate (Master's & Ph.D.) | 2017-22 |
| Varsha Chowdary Anche | Graduate (Ph.D.) | 2019-24 |
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